In 1997, The St La Salle Pre School was established by Andrew Benjamin Gonzalez FSC PhD through College of Education as an outreach program.

In 2006, The Old St La Salle Preschool was operated at the Leveriza Compound.

August 11, 2008, De La Salle University (DLSU) President and Chancellor Br.Armin Luistro FSC and De La Salle-College of St. Benilde (DLS-CSB) President Br. Victor Franco FSC signed a Memorandum of Cooperation last August 11 to formalize their joint support for the St. La Salle Preschool (SLSP).
The new Pre School building was constructed on the College of St Benilde real estate. It has a larger classroom with a reading corner and play area, a faculty room, and comfort rooms.
